DNA Replication: Light and Hybrid — NEET Biology

Which of the following statements regarding the modes of DNA replication and Meselson and Stahl's experiment are NOT correct? S1: If DNA replication were conservative, the first generation of E. coli grown in 14N medium after transfer from 15N would show two distinct bands (heavy and light) in a CsCl density gradient. S2: In a dispersive mode of DNA replication, after two generations in a 14N medium, all DNA molecules would still exhibit a single, albeit lighter, intermediate density band. S3: Meselson and Stahl's experiment established that 15N, a radioactive isotope of nitrogen, allowed for the differentiation of DNA molecules based on their density. S4: The observation of DNA with intermediate density after one generation in the 14N medium supported the hypothesis of conservative DNA replication. S5: The final results of Meselson and Stahl's experiment with E. coli conclusively demonstrated that DNA replication is semi-conservative, with each new molecule containing one parental and one newly synthesized strand.