Class 12 · Molecular Basis of Inheritance

Structural Differences Between RNA and DNA — NEET Biology

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In RNA, every nucleotide residue has an additional -OH group present at 2'-position in the ribose. Also, in RNA the uracil is found at the place of thymine (5-methyl uracil, another chemical name for thymine).

NCERT Biology · Class 12 · Chapter 5 · Paragraph 7
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Match the following features in Column I with the correct nucleic acid in Column II. Column I (Feature) A. Contains an additional -OH group at 2′-position of ribose B. Possesses thymine at the place of uracil C. Functions as the genetic material in the majority of organisms D. Known to exhibit catalytic activity (ribozyme) E. Exhibits a faster mutation rate due to inherent instability Column II (Nucleic Acid) I. DNA II. RNA

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Correct answer: D A-II, B-I, C-I, D-II, E-II

The core concept tested is the distinguishing features of DNA and RNA. Let's match each feature from Column I with the correct nucleic acid in Column II: A. Contains an additional -OH group at 2'-position of ribose: This is a characteristic of RNA (ribose sugar). So, A-II. B. Possesses thymine at the place of uracil: Thymine is present in DNA, while uracil is in RNA. So, B-I. C. Functions as the genetic material in the majority of organisms: DNA acts as the genetic material in most organisms. So, C-I. D. Known to exhibit catalytic activity (ribozyme): RNA molecules (ribozymes) can act as catalysts. So, D-II. E. Exhibits a faster mutation rate due to inherent instability: RNA is chemically less stable and mutates at a faster rate. So, E-II. Therefore, the correct match is A-II, B-I, C-I, D-II, E-II. Incorrect options: B. Incorrectly maps A, C, D, E. C. Incorrectly maps C and E. D. Incorrectly maps A, B, C. The final answer is D. Recap: Key differences between RNA and DNA include the presence of 2'-OH in RNA, thymine in DNA (uracil in RNA), DNA's role as primary genetic material in most organisms, RNA's catalytic activity, and RNA's higher mutation rate.

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What does NCERT say about RNA every nucleotide residue?
In RNA, every nucleotide residue has an additional -OH group present at 2'-position in the ribose. Also, in RNA the uracil is found at the place of thymine (5-methyl uracil, another chemical name for thymine).
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Molecular Basis of Inheritance, Class 12 NCERT Biology.

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