Class 12 · Principles of Inheritance and Variation

Chromosome Theory of Inheritance — NEET Biology

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In 1900, three Scientists (de Vries, Correns and von Tschermak) independently rediscovered Mendel's results on the inheritance of characters. Also, by this time due to advancements in microscopy that were taking place, scientists were able to carefully observe cell division. This led to the discovery of structures in the nucleus that appeared to double and divide just before each cell division. These were called chromosomes (colored bodies, as they were visualised by staining). By 1902, the chromosome movement during meiosis had been worked out. Walter Sutton and Theodore Boveri noted that the behaviour of chromosomes was parallel to the behaviour of genes and used chromosome movement to explain Mendel's laws (Table 4.3). Recall that you have studied the behaviour of chromosomes during mitosis (equational division) and during meiosis (reduction division). The important things to remember are that chromosomes as well as genes occur in pairs. The two alleles of a gene pair are located on homologous sites on homologous chromosomes.

🖼️Related NCERT figure: A diagram showing meiosis and germ cell formation in a cell with four chromosomes. The diagram shows the progression through G₁, G₂, Meiosis I anaphase, Meiosis II anaphase, and final Germ cells formation. Each stage shows chromosomes with different colored segments (yellow, orange, red, green) representing different alleles, demonstrating how chromosomes segregate during meiotic divisions. (Figure 4.8 Meiosis and germ cell formation in a cell with four chromosomes. Can you see how chromosomes segregate when germ cells are formed?)
NCERT Biology · Class 12 · Chapter 4 · Paragraph 56
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