Class 12 · Principles of Inheritance and Variation

Linkage: When Genes Segregate Together — NEET Biology

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Morgan carried out several dihybrid crosses in Drosophila to study genes that were sex-linked. The crosses were similar to the dihybrid crosses carried out by Mendel in peas. For example Morgan hybridised yellow-bodied, white-eyed females to brown-bodied, red-eyed males and intercrossed their F₁ progeny. He observed that the two genes did not segregate independently of each other and the F₂ ratio deviated very significantly from the 9:3:3:1 ratio (expected when the two genes are independent).

NCERT Biology · Class 12 · Chapter 4 · Paragraph 60
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Q10. If in a dihybrid F₂ generation, the observed ratio deviates from 9:3:3:1, what could be a likely reason?

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Correct answer: B Linkage between genes

Linked genes do not assort independently and thus distort expected 9:3:3:1 ratios.

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Morgan carried out several dihybrid crosses in Drosophila to study genes that were sex-linked. The crosses were similar to the dihybrid crosses carried out by Mendel in peas.
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Principles of Inheritance and Variation, Class 12 NCERT Biology.

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