Nodal Tissue: SAN, AVN and Purkinje Fibres

Biology · Body Fluids and Circulation · NEET

Nodal tissue is specialised cardiac muscle that makes and carries the heart's own electric signal. It has 5 parts in order: SAN (in the right upper corner of the right atrium) starts the beat, then AVN (lower left of the right atrium), then the AV bundle (bundle of His), then the right and left bundle branches, and finally the Purkinje fibres in the ventricle walls. Memory hook: "So All Boys Play Cricket" = SAN, AVN, Bundle (of His), bundle Branches, Purkinje.
Cardiac Nodal Tissue and Conduction PathwaySAN(right upper)AVNAV bundle (His)Bundle branchesPurkinje fibresOrder of impulse:1. SAN (pacemaker, 70-75/min)2. AVN (delay ~0.1 s)3. AV bundle (His)4. Bundle branches (R and L)5. Purkinje fibres
Nodal tissue in the heart and the fixed conduction order: SAN starts the beat, AVN delays it ~0.1 s, then the AV bundle, bundle branches and Purkinje fibres spread the signal so the ventricles contract together.

Your doubts, answered

Is nodal tissue nerve or muscle?

It is MUSCLE, not nerve. NCERT calls it 'a specialised cardiac musculature called the nodal tissue.' Because the beat starts inside this muscle and not from any nerve, the heart is said to be myogenic. This is a very common NEET trap: nodal tissue is modified cardiac muscle, so it can contract and also generate its own action potential (autoexcitable).

Where exactly are the SAN and AVN located?

SAN (sino-atrial node) is a patch of nodal tissue in the RIGHT UPPER corner of the RIGHT atrium. AVN (atrio-ventricular node) is another mass in the LOWER LEFT corner of the RIGHT atrium, close to the atrio-ventricular septum. Note both are in the right atrium. Students often wrongly place the AVN in the left atrium; it is in the right atrium near the septum.

What is the difference between the AVN and the AV bundle?

AVN (atrio-ventricular node) is the node that receives the signal from the SAN and briefly delays it. The AV bundle (bundle of His) is the conducting cable that continues FROM the AVN, passes through the atrio-ventricular septum, and then divides into the right and left bundle branches. So AVN = the node; AV bundle = the tract leaving that node.

What are Purkinje fibres and what do they do?

Purkinje fibres are the final, finely branched part of the nodal tissue spread throughout the walls of the ventricles. The bundle branches carry the impulse down to the heart apex, and there they continue as Purkinje fibres, which quickly spread the signal to the whole ventricular muscle so both ventricles contract together and pump blood out.

Why does the AVN delay the impulse by about 0.1 second?

The short AVN delay lets atrial contraction (atrial systole) finish first, so the atria empty their blood completely into the ventricles before the ventricles begin to contract. This timing gap makes pumping efficient. A NEET 2019 question tested exactly this: the delay allows 'the atria to empty completely.'

What is the correct sequence of conduction?

SAN → AVN → AV bundle (bundle of His) → right and left bundle branches → Purkinje fibres → ventricular muscle. NEET 2024 asked this order and the answer was E-C-A-D-B (SA node, AV node, AV bundle, bundle branches, Purkinje fibres). Learn this exact order.

⚠️ The NEET trap
The AVN generates the impulse that starts the heartbeat, so the AVN is the pacemaker.
The SAN starts the heartbeat and is the pacemaker; the AVN only receives and relays the signal from the SAN.
🧠 NTA loves this swap. The SAN fires first (fastest depolarisation, 70-75 action potentials/min). The AVN's job is to briefly delay and pass on the signal, not to start it. If a statement says 'AVN generates the action potential to stimulate contraction,' it is FALSE (tested in NEET 2022/2023).

Real NEET questions

2019

A specialised nodal tissue embedded in the lower corner of the right atrium, close to Atrio-ventricular septum, delays the spreading of impulses to heart apex for about 0.1 sec. The delay allows:

A · blood to enter aorta.
B · the ventricles to empty completely.
C · blood to enter pulmonary arteries.
D · the atria to empty completely.
Solution: The tissue described is the atrio-ventricular node (AVN). Its brief conduction delay lets atrial systole finish first, so the atria empty their blood completely into the ventricles before the ventricles contract.
2024

Following are the stages of pathway for conduction of an action potential through the heart: A. AV bundle B. Purkinje fibres C. AV node D. Bundle branches E. SA node. Choose the correct sequence of pathway.

A · A-E-C-B-D
B · B-D-E-C-A
C · E-A-D-B-C
D · E-C-A-D-B
Solution: The impulse starts in the SA node (E), goes to the AV node (C), then the AV bundle (A), which divides into right and left bundle branches (D), and finally spreads via Purkinje fibres (B). Correct order: E-C-A-D-B.
2022

Which one of the following statements is correct?

A · The atrioventricular node (AVN) generates an action potential to stimulate atrial contraction
B · The tricuspid and the bicuspid valves open due to the pressure exerted by the simultaneous contraction of the atria
C · Blood moves freely from atrium to the ventricle during joint diastole
D · Increased ventricular pressure causes closing of the semilunar valves
Solution: During joint diastole all chambers relax and the AV valves are open, so blood flows freely from atria into ventricles. The SAN (not AVN) generates the impulse, so option A is wrong; this is the classic AVN-as-pacemaker trap.

Solved Body Fluids and Circulation NEET PYQs

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Frequently asked

Why is the heart called myogenic?

Because the beat is auto-regulated by specialised muscle (the nodal tissue), not by any nerve. The signal is made inside the heart muscle itself, so the heart is myogenic. A frog's heart even keeps beating for a while after it is removed from the body.

How many action potentials does the SAN generate per minute?

About 70-75 per minute. This is the highest rate among all nodal parts, which is why the SAN sets the pace and is called the pacemaker (giving a resting heart rate of around 72 beats/min).

What is the bundle of His?

The bundle of His is the atrio-ventricular bundle (AV bundle). It continues from the AVN, passes through the atrio-ventricular septum, and then splits into the right and left bundle branches that carry the impulse toward the ventricles.

Are all parts of the nodal tissue autoexcitable?

Yes. All components of the nodal tissue can generate their own action potentials (autoexcitable). But the SAN depolarises fastest, so it dominates and the others follow its rhythm.