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NEET 2018 · BiologyPrevious Year Question

Which of the following is not an autoimmune disease?

Answer: (A) Alzheimer's disease. Answer: (A) Alzheimer's disease Solution: Autoimmune diseases result when the body's immune system attacks self-cells.

  1. A.Alzheimer's disease✓
  2. B.Rheumatoid arthritis
  3. C.Psoriasis
  4. D.Vitiligo

Correct Answer

(A) Alzheimer's disease

Solution & Explanation

Answer: (A) Alzheimer's disease Solution: Autoimmune diseases result when the body's immune system attacks self-cells. Rheumatoid arthritis is given by NCERT as an example of an auto-immune disease; psoriasis and vitiligo are also autoimmune/immune-mediated disorders. Alzheimer's disease is a neurodegenerative disorder caused by progressive loss of neurons (amyloid plaques and tangles), not by the immune system attacking self-cells, so it is NOT an autoimmune disease. Why the others are autoimmune: NCERT explicitly names rheumatoid arthritis as autoimmune; psoriasis and vitiligo are both caused by immune attack on the body's own skin/tissue, making A the exception. NCERT Reference: NCERT Ch7, p.137, lines 33-34: "Rheumatoid arthritis which affects many people in our society is an auto-immune disease"

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