NEET 2018 · BiologyPrevious Year Question
Which of the following is commonly used as a vector for introducing a DNA fragment in human lymphocytes?
Answer: (C) Retrovirus. Answer: (3) Retrovirus Solution: Human lymphocytes are animal cells, and the disarmed retroviruses are the vectors used to deliver desirable genes into animal cells.
- A.λ phage
- B.Ti plasmid
- C.Retrovirus✓
- D.pBR 322
Correct Answer
(C) Retrovirus
Solution & Explanation
Answer: (3) Retrovirus Solution: Human lymphocytes are animal cells, and the disarmed retroviruses are the vectors used to deliver desirable genes into animal cells. lambda phage and pBR322 are vectors used in bacteria (E. coli), while the Ti plasmid of Agrobacterium is used to transform plant cells. Hence the retrovirus is the appropriate vector for human (animal) lymphocytes. NCERT Reference: Ch 9, p.170, line(s) 37 — "retroviruses have also been disarmed and are now used to deliver desirable genes into animal cells"
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