What is the genetic disorder in which an individual has an overall masculine development, gynaecomastia, and is sterile?
Answer: (B) Klinefelter's syndrome. Answer: (B) Klinefelter's syndrome Solution: Klinefelter's syndrome (karyotype 47, XXY) arises from an additional X-chromosome.
- A.Turner's syndrome
- B.Klinefelter's syndrome✓
- C.Edward syndrome
- D.Down's syndrome
Correct Answer
(B) Klinefelter's syndrome
Solution & Explanation
Answer: (B) Klinefelter's syndrome Solution: Klinefelter's syndrome (karyotype 47, XXY) arises from an additional X-chromosome. The affected individual has overall masculine development but also expresses feminine development such as gynaecomastia (development of breast), and such individuals are sterile. This exactly matches the description given. NCERT Reference: NCERT Class XII, Ch 4, p.76, lines 028-034: "Klinefelter’s Syndrome : This genetic disorder is also caused due to the presence of an additional copy of X- chromosome resulting into a karyotype of 47, XXY. Such an individual has overall masculine development, however, the feminine development (development of breast, i.e., Gynaecomastia) is also expressed... Such individuals are sterile."