Which of the following statements are correct about Klinefelter's Syndrome? A. This disorder was first described by Landon Down (1866). B. Such an individual has overall masculine development. However, the feminine development is also expressed. C. The affected individual is short statured. D. Physical, psychomotor and mental development is retarded. E. Such individuals are sterile. Choose the correct answer from the options given below:

Solution & Explanation

Answer: (C) B and E only Solution: For Klinefelter's Syndrome (47, XXY): statement B is correct (overall masculine development with some feminine development/gynaecomastia) and statement E is correct (such individuals are sterile). Statement A is false (it describes Down's syndrome, first described by Langdon Down 1866). Statements C and D (short stature; retarded physical, psychomotor and mental development) describe Down's syndrome, not Klinefelter's. Hence only B and E are correct. NCERT Reference: NCERT Class XII, Ch 4, p.76, lines 30-34: "resulting into a karyotype of 47, XXY. Such an individual has overall masculine development, however, the feminine development (development of breast, i.e., Gynaecomastia) is also expressed (Figure 4.17 a). Such individuals are sterile."