In which blood corpuscles, the HIV undergoes replication and produces progeny viruses?
Answer: (A) TH cells. Answer: (A) TH cells Solution: After HIV enters the body it first infects macrophages, but it also enters helper T-lymphocytes (TH), where it replicates and produces progeny viruses that go on to attack other helper T-cells.
- A.TH cells✓
- B.B-lymphocytes
- C.Basophils
- D.Eosinophils
Correct Answer
(A) TH cells
Solution & Explanation
Answer: (A) TH cells Solution: After HIV enters the body it first infects macrophages, but it also enters helper T-lymphocytes (TH), where it replicates and produces progeny viruses that go on to attack other helper T-cells. This progressive destruction of TH cells causes the immunodeficiency. Why others are wrong: B-lymphocytes, basophils and eosinophils are not the cells in which HIV replicates to release progeny — NCERT specifically names helper T-lymphocytes. NCERT Reference: NCERT Ch7, p.140, lines 8-11: "HIV enters into helper T-lymphocytes (TH), replicates and produce progeny viruses"