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NEET 2023 Phase 2 · BiologyPrevious Year Question

Which of the following statements is not correct?

Answer: (A) The functional insulin has A and B chains linked together by hydrogen bonds. Answer: (A) The functional insulin has A and B chains linked together by hydrogen bonds Solution: Insulin's A and B chains are linked by disulphide bridges, not hydrogen bonds — so statement (A) is the incorrect (not correct) one.

  1. A.The functional insulin has A and B chains linked together by hydrogen bonds✓
  2. B.Genetically engineered insulin is produced in E-Coli
  3. C.In man insulin is synthesised as a proinsulin
  4. D.The proinsulin has a extra peptide called C-peptide

Correct Answer

(A) The functional insulin has A and B chains linked together by hydrogen bonds

Solution & Explanation

Answer: (A) The functional insulin has A and B chains linked together by hydrogen bonds Solution: Insulin's A and B chains are linked by disulphide bridges, not hydrogen bonds — so statement (A) is the incorrect (not correct) one. The other statements are true: Eli Lilly produced genetically engineered insulin chains in E. coli; in humans insulin is first made as a pro-hormone (proinsulin); proinsulin carries an extra stretch called the C peptide that is removed on maturation. NCERT Reference: Ch 10, p.181, line 026 — "and chain B, that are linked together by disulphide bridges"

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