NEET 2023 Phase 2 · BiologyPrevious Year Question
Select incorrect statement, regarding chemical structure of insulin. (NEET 2023 (Phase 2))
Answer: (C) Mature insulin molecule consists of three polypeptide chains - A, B and C.. Answer: (3) Mature insulin molecule consists of three polypeptide chains - A, B and C.
- A.C-peptide is not present in mature insulin molecule.
- B.Polypeptide chains A and B are linked by disulphide bridges.
- C.Mature insulin molecule consists of three polypeptide chains - A, B and C.✓
- D.Insulin is synthesized as prohormone which contains extra stretch of C-peptide.
Correct Answer
(C) Mature insulin molecule consists of three polypeptide chains - A, B and C.
Solution & Explanation
Answer: (3) Mature insulin molecule consists of three polypeptide chains - A, B and C. Solution: Mature insulin consists of only TWO polypeptide chains (A and B) linked by disulphide bridges; the C-peptide is removed during maturation and is absent in mature insulin, so statement (3) is incorrect. Statements (1), (2) and (4) are all correct per NCERT. NCERT Reference: Ch 10, p.181, line 26 — "Insulin consists of two short polypeptide chains: chain A"
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