The other type of macromolecule that one would find in the acid insoluble fraction of any living tissue is the nucleic acid. These are polynucleotides. Together with polysaccharides and polypeptides these comprise the true macromolecular fraction of any living tissue or cell. For nucleic acids, the building block is a nucleotide. A nucleotide has three chemically distinct components. One is a heterocyclic compound, the second is a monosaccharide and the third a phosphoric acid or phosphate.
Which of the following statements are correct about biomacromolecules and related concepts? S1: Proteins are homopolymers made of only one type of monomer repeating ‘n’ number of times. S2: Collagen is the most abundant protein in the animal world, while RuBisCO is the most abundant protein in the whole of the biosphere. S3: Polysaccharides like cellulose are homopolymers of glucose, whereas starch is a heteropolymer with different monosaccharides. S4: The right end of a polysaccharide chain is called the reducing end, and the left end is called the non-reducing end. S5: Nucleic acids are polynucleotides where the building block, a nucleotide, consists of a heterocyclic compound, a monosaccharide, and a phosphate group. S6: Lipids are considered true macromolecules due to their high molecular weight, similar to proteins and nucleic acids.
Correct answer: B — S2, S4 and S5 are correct
Let's evaluate each statement based on the NCERT text: S1: "Each protein is a polymer of amino acids. As there are 20 types of amino acids (e.g., alanine, cysteine, proline, tryptophan, lysine, etc.), a protein is a heteropolymer and not a homopolymer." This statement is incorrect. S2: "Collagen is the most abundant protein in animal world and Ribulose bisphosphate Carboxylase-Oxygenase (RuBisCO) is the most abundant protein in the whole of the biosphere." This statement is correct. S3: "For example, cellulose is a polymeric polysaccharide consisting of only one type of monosaccharide i.e., glucose. Cellulose is a homopolymer. Starch is a variant of this but present as a store house of energy in plant tissues." This statement is incorrect as starch is also a homopolymer of glucose, not a heteropolymer. S4: "In a polysaccharide chain (say glycogen), the right end is called the reducing end and the left end is called the non-reducing end." This statement is correct. S5: "For nucleic acids, the building block is a nucleotide. A nucleotide has three chemically distinct components. One is a heterocyclic compound, the second is a monosaccharide and the third a phosphoric acid or phosphate." This statement is correct. S6: "Lipids are indeed small molecular weight compounds... Lipids are not strictly macromolecules." This statement is incorrect because lipids are not strictly macromolecules based on their molecular weight, although they are found in the acid-insoluble fraction due to their aggregation into vesicles. Therefore, statements S2, S4, and S5 are correct. The final answer is B. Recap: This question assesses the understanding of key characteristics of various biomacromolecules like proteins, polysaccharides, and nucleic acids, including their polymeric nature, building blocks, and exceptions like lipids.
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