Transgenic Mice in Vaccine Safety Testing — NEET Biology
🔥 Predicted for NEET 2027Vaccine safety: Transgenic mice are being developed for use in testing the safety of vaccines before they are used on humans. Transgenic mice are being used to test the safety of the polio vaccine. If successful and found to be reliable, they could replace the use of monkeys to test the safety of batches of the vaccine.
Adjacent to a frequently-asked paragraph in the same chapter.
Match the Column – Column I A. Study of diseases B. Biological product synthesis C. Vaccine safety testing D. Toxicity testing Column II i. Sensitivity to toxic substances ii. Polio vaccine tested on transgenic mice iii. Rosie cow producing human protein iv. Transgenic mice models for cancer
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Correct answer: D — A–iv, B–iii, C–ii, D–i
Transgenic mice are used to study diseases such as cancer because specific human genes can be introduced to observe disease progression. The Rosie cow was engineered to produce human proteins, showing the use of transgenic animals in biological product synthesis. Transgenic mice are also used to test the safety of vaccines like the polio vaccine before human use. Some transgenic animals are designed with heightened sensitivity to toxic substances, making them useful in toxicity testing.
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