Class 11 · Cell: The Unit of Life

Nucleolus: rRNA Synthesis Site — NEET Biology

✅ Asked in NEET 2026
📖 NCERT Source

The nuclear matrix or the nucleoplasm contains nucleolus and chromatin. The nucleoli are spherical structures present in the nucleoplasm. The content of nucleolus is continuous with the rest of the nucleoplasm as it is not a membrane bound structure. It is a site for active ribosomal RNA synthesis. Larger and more numerous nucleoli are present in cells actively carrying out protein synthesis.

NCERT Biology · Class 11 · Chapter 8 · Paragraph 68
How NTA Uses This Concept

The nucleolus is a non-membrane-bound structure within the nucleus that actively synthesizes ribosomal RNA (rRNA). NTA tests whether students understand that the nucleolus is specifically dedicated to rRNA production, not all types of RNA. Students often confuse nucleolus function with the nucleus itself or incorrectly associate it with mRNA or tRNA synthesis. The key to answering correctly: remember that nucleoli are more prominent in protein-synthesizing cells because these cells need more ribosomes. When a question asks about the site of rRNA synthesis or why metabolically active cells have larger nucleoli, the answer is always the nucleolus.

Solve This NEET Question

This paragraph was tested 3 times in NEET.

Q1 of 3NEET 2026 (cancelled)

Which one of the following is the site for active ribosomal RNA synthesis?

Q2 of 3NEET 2024

Match List I with List II. List-I A. Nucleolus B. Centriole C. Leucoplasts D. Golgi apparatus List-II I. Site of formation of glycolipid II. Organization like the cartwheel III. Site of active ribosomal RNA synthesis IV. For storing nutrients

Q3 of 3NEET 2018

Which of the following is true for the nucleolus? NEET 2018

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