Glucagon: The Hyperglycemic Hormone — NEET Biology
📚 Practice ConceptGlucagon is a peptide hormone, and plays an important role in maintaining the normal blood glucose levels. Glucagon acts mainly on the liver cells (hepatocytes) and stimulates glycogenolysis resulting in an increased blood sugar (hyperglycaemia). In addition, this hormone stimulates the process of gluconeogenesis which also contributes to hyperglycemia. Glucagon reduces the cellular glucose uptake and utilisation. Thus, glucagon is a hyperglycemic hormone.
Which of the following statements correctly describes the interplay of hormones in maintaining blood glucose homeostasis? S1: Insulin promotes hyperglycemia by increasing glucose synthesis in the liver. S2: Glucagon stimulates gluconeogenesis and glycogenolysis, both contributing to increased blood glucose. S3: The glucose homeostasis in blood is maintained jointly by insulin and glucagon. S4: A deficiency of glucagon would lead to prolonged hyperglycemia and formation of ketone bodies. S5: Insulin reduces cellular glucose uptake, whereas glucagon enhances it.
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