What is the mechanism by which the AIDS virus causes deficiency of immune system of the infected person?
Which of the following statements regarding the progression and impact of HIV infection on the human immune system are correct? S1: HIV infection leads to a progressive decrease in the number of helper T-lymphocytes. S2: Macrophages, once infected, serve as a 'HIV factory', continuously producing new viral particles. S3: The severe immunodeficiency in AIDS patients results in susceptibility to opportunistic infections like Mycobacterium and Toxoplasma. S4: B-lymphocytes are directly targeted and destroyed by HIV, impairing the humoral immune response. S5: The initial low-intensity immune response upon first encounter with HIV is characteristic of active immunity.
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