Genetic Testing for Cancer Susceptibility — NEET Biology
📚 Practice ConceptIdentification of such genes, which predispose an individual to certain cancers, may be very helpful in prevention of cancers. Such individuals may be advised to avoid exposure to particular carcinogens to which they are susceptible (e.g., tobacco smoke in case of lung cancer).
Which of the following statements are correct regarding carcinogens and oncogenes? S1: Oncogenic viruses are biological carcinogens that carry genes known as viral oncogenes. S2: Chemical carcinogens present in tobacco smoke are a major cause of lung cancer, while UV rays are a type of ionizing radiation. S3: Proto-oncogenes (c-onc) are normally regulated genes in cells which, upon activation under specific conditions, can contribute to oncogenic transformation. S4: All physical carcinogens lead to cancer by directly binding to specific receptors on cell surfaces. S5: Identification of genes predisposing an individual to certain cancers can guide recommendations to avoid exposure to specific carcinogens.
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