The mitotic division starts as the zygote moves through the isthmus of the oviduct called cleavage towards the uterus and forms 2, 4, 8, 16 daughter cells called blastomeres. The embryo with 8 to 16
Arrange the following events of human reproduction and embryonic development in the correct chronological sequence: (A) Differentiation of inner cell mass into germ layers (B) Formation of zygote (C) Blastocyst formation and its attachment to the uterine wall (D) Appearance of limbs and digits (E) Cleavage divisions leading to morula (F) Formation of chorionic villi from trophoblast
Correct answer: A — B → E → C → A → F → D
This question requires arranging key events in human reproduction and embryonic development in their correct chronological order. 1. **(B) Formation of zygote:** This is the first event, resulting from the fusion of male and female gametes during fertilisation (Section 2.5). 2. **(E) Cleavage divisions leading to morula:** The zygote undergoes mitotic divisions (cleavage) as it moves through the oviduct, forming 2, 4, 8, 16 daughter cells called blastomeres, eventually forming a morula (Section 2.5). 3. **(C) Blastocyst formation and its attachment to the uterine wall:** The morula continues to divide and transforms into a blastocyst, which then attaches to the endometrium (implantation) (Section 2.5). 4. **(A) Differentiation of inner cell mass into germ layers:** Immediately after implantation, the inner cell mass differentiates into ectoderm, endoderm, and mesoderm (germ layers) (Section 2.6). 5. **(F) Formation of chorionic villi from trophoblast:** After implantation, finger-like projections appear on the trophoblast called chorionic villi (Section 2.6). 6. **(D) Appearance of limbs and digits:** This is a later developmental milestone; by the end of the second month of pregnancy, the foetus develops limbs and digits (Section 2.6). Therefore, the correct chronological sequence is B → E → C → A → F → D.
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