Class 12 · Molecular Basis of Inheritance

tRNA as Adapter Molecule — NEET Biology

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From the very beginning of the proposition of code, it was clear to Francis Crick that there has to be a mechanism to read the code and also to link it to the amino acids, because amino acids have no structural specialties to read the code uniquely. He postulated the presence of an adapter molecule that would on one hand read the code and on other hand would bind to specific amino acids. The tRNA, then called sRNA (soluble RNA), was known before the genetic code was postulated. However, its role as an adapter molecule was assigned much later.

📐See NCERT Figure 5.12 for the diagram.
NCERT Biology · Class 12 · Chapter 5 · Paragraph 115
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QuestionPractice Question

Which molecule was proposed by Crick to act as an adaptor during translation?

📖 Solution & NCERT Explanation
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Correct answer: B tRNA

Crick’s adaptor hypothesis described tRNA as the adaptor between codon and amino acid.

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From the very beginning of the proposition of code, it was clear to Francis Crick that there has to be a mechanism to read the code and also to link it to the amino acids, because amino acids have no structural specialties to read the code uniquely. He postulated the presence of an adapter molecule that would on one hand read the code and on other hand would bind to specific amino acids.
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Molecular Basis of Inheritance, Class 12 NCERT Biology.

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