Class 12 · Molecular Basis of Inheritance

Protein Synthesis: Initiation, Elongation, Termination — NEET Biology

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For initiation, the ribosome binds to the mRNA at the start codon (AUG) that is recognised only by the initiator tRNA. The ribosome proceeds to the elongation phase of protein synthesis. During this stage, complexes composed of an amino acid -linked to tRNA, sequentially bind to the appropriate codon in mRNA by forming complementary base pairs with the tRNA anticodon. The ribosome moves from codon to codon along the mRNA. Amino acids are added one by one, translated into Polypeptide sequences dictated by DNA and represented by mRNA. At the end, a release factor binds to the stop codon, terminating translation and releasing the complete polypeptide from the ribosome.

NCERT Biology · Class 12 · Chapter 5 · Paragraph 120
Why This May Be Tested in NEET 2027

Adjacent to a frequently-asked paragraph in the same chapter.

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QuestionPredicted for NEET 2027

Refer to the figure. What ensures the correct sequence of amino acids during polypeptide formation?

📖 Solution & NCERT Explanation
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Correct answer: C Complementarity between tRNA and mRNA

tRNAs bring specific amino acids by base-pairing their anticodons with mRNA codons, ensuring correct amino acid sequence in the polypeptide.

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What does NCERT say about For initiation ribosome binds?
For initiation, the ribosome binds to the mRNA at the start codon (AUG) that is recognised only by the initiator tRNA. The ribosome proceeds to the elongation phase of protein synthesis.
Has this concept appeared in NEET?
High probability for NEET 2027. Adjacent to a frequently-asked paragraph in the same chapter.
Which chapter is this from?
Molecular Basis of Inheritance, Class 12 NCERT Biology.

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