Class 12 · Molecular Basis of Inheritance

Chargaff's Rules & Base Pairing — NEET Biology

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If a double stranded DNA has 20 per cent of cytosine, calculate the per cent of adenine in the DNA.

NCERT Biology · Class 12 · Chapter 5 · Paragraph 163
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Which of the above statements regarding DNA structure and base pairing are correct? S1: Guanine and Cytosine form three hydrogen bonds, making their interaction stronger than Adenine-Thymine pairing. S2: The complementary base pairing rules ensure that a purine always pairs with a pyrimidine, maintaining a uniform diameter of the DNA double helix. S3: Base stacking interactions between adjacent base pairs also contribute significantly to the stability of the double helical DNA structure. S4: The strength of hydrogen bonds between base pairs is the sole factor conferring stability to the DNA double helix. S5: In a double-stranded DNA molecule, the ratio of purines to pyrimidines is always one, according to Chargaff’s rule.

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