DNA Base Pairing & Semi-Conservative Replication — NEET Biology
📚 Practice ConceptWhich property of DNA double helix led Watson and Crick to hypothesise semi-conservative mode of DNA replication? Explain.
Which of the above statements regarding the historical discoveries and properties of genetic material are correct? S1: Watson and Crick utilized X-ray diffraction data produced by Maurice Wilkins and Rosalind Franklin to propose the double helix model of DNA. S2: Friedrich Meischer first identified DNA as an acidic substance in the nucleus and correctly concluded its role as the transforming principle. S3: Hershey and Chase definitively proved DNA as the genetic material by observing radioactive sulfur (35S) in infected bacterial cells after phage infection. S4: Meselson and Stahl's experiment demonstrated the semi-conservative replication of DNA by using heavy nitrogen (15N). S5: Avery, MacLeod, and McCarty purified biochemicals from heat-killed S cells and found that DNA alone caused R bacteria to become transformed.
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