List two essential roles of ribosome during translation.
Which of the following statements about ribosomes and translation are correct? S1: A polyribosome consists of several ribosomes attached to a single mRNA, enabling simultaneous translation into multiple polypeptide chains. S2: In prokaryotes, transcription and translation can occur simultaneously because there is no spatial separation between the nucleus and the cytoplasm. S3: The P-site and A-site for tRNA binding are located on the small ribosomal subunit, facilitating the addition of amino acids. S4: The 23S rRNA in bacteria exhibits catalytic activity, acting as a ribozyme during peptide bond formation. S5: Untranslated regions (UTRs) are present only at the 5'-end of the mRNA, preceding the start codon, and are essential for efficient translation.
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