Molecular Inheritance: Transcription & Translation — NEET Biology

Which of the following statements correctly describe the coupling of transcription and translation, particularly in prokaryotes? S1: The coupling of transcription and translation in prokaryotes is primarily attributed to the mRNA's extensive post-transcriptional modifications. S2: In prokaryotes, ribosomes attach to the nascent mRNA and initiate protein synthesis only after the complete transcription of the gene. S3: The absence of a nuclear membrane, allowing both processes to occur in the cytoplasm, is a key factor enabling transcription-translation coupling in bacteria. S4: Eukaryotic transcription and translation are spatially and temporally separated, primarily due to the processing requirements of hnRNA and its transport out of the nucleus. S5: The prokaryotic mRNA typically does not require splicing, which is a prerequisite for coupling transcription and translation.