Moreover, he recovered living S bacteria from the dead mice.
Arrange the following experimental observations of Frederick Griffith’s Transforming Principle in the correct chronological sequence: 1. Mice injected with R strain → mice survived. 2. Mice injected with heat-killed S strain → mice survived. 3. Mice injected with S strain → mice died of pneumonia. 4. Mice injected with heat-killed S strain + live R strain → mice died, and living S strain was recovered
Correct answer: C — 3 → 1 → 2 → 4
Griffith first showed that S strain killed mice (virulent). Next, R strain was harmless → mice survived. Then, heat-killed S strain failed to kill mice. Finally, the mixture of heat-killed S + live R killed mice, and live S bacteria were recovered → proof of transforming principle.
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