DNA Replication Model by Watson-Crick — NEET
📚 Practice ConceptWhile proposing the double helical structure for DNA, Watson and Crick had immediately proposed a scheme for replication of DNA. To quote their original statement that is as follows:
Which of the following statements regarding the structure and replication of DNA are correct? S1: Watson and Crick's proposition of DNA replication immediately followed their elucidation of the double helix structure, suggesting a copying mechanism for genetic material. S2: The chemical stability of DNA is enhanced by the presence of a 2'-OH group at every nucleotide, making it less reactive than RNA. S3: Complementary base pairing ensures that each parental DNA strand can accurately serve as a template for synthesizing new identical strands, leading to semiconservative replication. S4: DNA-dependent DNA polymerases can initiate the process of replication at any random location along the DNA molecule. S5: The experimental proof for semiconservative DNA replication was first demonstrated in higher organisms like Vicia faba, and later confirmed in prokaryotes like E. coli.
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