The DNA polymerases on their own cannot initiate the process of replication. Also the replication does not initiate randomly at any place in DNA. There is a definite region in E. coli DNA where the replication originates. Such regions are termed as origin of replication. It is
Adjacent to a frequently-asked paragraph in the same chapter.
Given below are four statements: A. The semi-conservative model of DNA replication was proved in E. coli using isotope labeling. B. The concept of Okazaki fragments is essential for explaining replication in the lagging strand. C. Spliceosomes are required to remove introns from hnRNA. D. The lac operon repressor protein binds directly to the promoter region.
Correct answer: C — 3
Statements A and B cover replication, C covers RNA processing, but D is wrong since the repressor binds the operator, not the promoter.
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