Class 12 · Molecular Basis of Inheritance

RNA Polymerase III and tRNA/snRNA — NEET Biology

✅ Asked in NEET 2024
📖 NCERT Source

The RNA polymerase II transcribes precursor of mRNA, the heterogeneous nuclear RNA (hnRNA).

NCERT Biology · Class 12 · Chapter 5 · Paragraph 85
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RNA Polymerase III specifically transcribes tRNA, 5S rRNA, and snRNAs, while RNA Pol II transcribes mRNA precursor (hnRNA), and RNA Pol I transcribes 28S, 18S, and 5.8S rRNA. Students often confuse which polymerase transcribes which RNA type, especially mixing up tRNA assignment between Pol II and Pol III. The key distinguishing feature: Pol III handles transfer RNA and small RNAs involved in splicing/translation. Remember: Pol I (large rRNAs), Pol II (mRNA/hnRNA), Pol III (tRNA/snRNA/5S rRNA). This appears repeatedly in NEET because it tests precise understanding of transcription machinery and RNA classification, making it high-yield for multiple-choice questions.

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This paragraph was tested 3 times in NEET.

Q1 of 3NEET 2024

Match List I with List II: A. RNA polymerase III B. Termination of transcription C. Splicing of exons D. TATA box List II I. snRNPs II. Promoter III. Rho factor IV. snRNAs, tRNA

Q2 of 3NEET 2023

What is the role of RNA polymerase III in the process of transcription in eukaryotes? (NEET 2023)

Q3 of 3NEET 2021

What is the role of RNA polymerase III in transcription in eukaryotes? (NEET 2021)

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