What Is Bt Cotton?

Biology · Biotechnology and Its Applications · NEET

Bt cotton is a genetically modified (GM) cotton plant that carries a toxin gene (a cry gene) taken from the soil bacterium Bacillus thuringiensis. Because the plant now makes its own Bt toxin, it becomes resistant to insect pests, mainly lepidopteran bollworms, so farmers need far less chemical insecticide. Memory hook: "Bt" = Bacillus thuringiensis; the plant becomes its own built-in bio-pesticide.
How Bt Cotton Is Made and WorksBacillusthuringiensiscry gene(cryIAc)Insert geneinto cottonBt cotton (GM)makes Bt toxinBollworm eats plant, toxinactivates in alkaline gut, pest diesResult: lessinsecticide needed
The cry gene (cryIAc) from Bacillus thuringiensis is inserted into cotton, making Bt cotton produce its own Bt toxin. When a bollworm eats the plant, the toxin activates in its alkaline gut and kills it, so far less chemical insecticide is needed.

Your doubts, answered

Is Bt cotton resistant to insects or to nematodes?

Bt cotton is resistant to INSECT PESTS, chiefly lepidopteran bollworms. It is NOT the strategy used against nematodes. Making plants nematode-resistant (for example against Meloidogyne incognita in tobacco roots) uses RNA interference (RNAi), a completely different method. NEET loves to swap these two, so remember: Bt = insect pest resistance; RNAi = nematode resistance.

Which gene is inserted into Bt cotton and where does it come from?

A cry gene (a Bt toxin gene) is taken from the soil bacterium Bacillus thuringiensis and inserted into cotton. The proteins encoded by cryIAc and cryIIAb control the cotton bollworms, while cryIAb controls corn borer. So for cotton specifically, cryIAc is the gene to remember.

Does Bt cotton kill every kind of insect?

No. Bt toxins are insect-group specific. A given Bt protein kills only certain insect groups, such as lepidopterans (bollworms, budworms), coleopterans (beetles) or dipterans (flies, mosquitoes). This is why different cry genes are used for different target pests, and why Bt cotton mainly protects against bollworms.

Why does Bt cotton need much less insecticide?

Because the plant itself produces the Bt toxin inside its tissues. When a bollworm eats the plant, the toxin activates in its gut and kills it. The crop carries its own bio-insecticide, so the farmer does not need to spray as much chemical insecticide.

Is Bt cotton a GMO?

Yes. Bt cotton is a genetically modified organism (GMO) because a foreign gene (the cry gene from Bacillus thuringiensis) has been added to the cotton plant using genetic engineering. It is one of the standard NCERT examples of a GM crop, along with Bt corn, Flavr Savr tomato and Golden rice.

⚠️ The NEET trap
Bt cotton is resistant to fungal diseases and to nematodes.
Bt cotton is resistant to INSECT PESTS (lepidopteran bollworms). Nematode resistance uses RNAi, not Bt; fungal resistance is not what the Bt gene does.
🧠 Bt = Bug (insect) killer. Nematode = RNAi. Keep the two defence strategies in separate boxes.

Real NEET questions

NEET 2020

Bt cotton variety that was developed by the introduction of toxin gene of Bacillus thuringiensis (bt) is resistant to:

A · Plant nematodes
B · Insect predators
C · Insect pest
D · Fungal diseases
Solution: The Bt toxin gene cloned from Bacillus thuringiensis is expressed in cotton to make it resistant to insect pests (chiefly lepidopteran bollworms), acting as a built-in bio-pesticide. It does not give resistance to nematodes (that is the RNAi strategy) or to fungal diseases, and 'insect predators' are beneficial insects, not the target. NCERT Ch 10, p.179.
NEET 2026

The toxin proteins isolated from Bacillus thuringiensis, coded by which of the following genes would control cotton bollworms and corn borer, respectively?

A · cryIAc and cryIAb
B · cryIAc and cryIIAb
C · cryIIAb and cryIAc
D · cryIAc and cryIIIAb
Solution: The proteins encoded by cryIAc (and cryIIAb) control the cotton bollworms, while the protein of cryIAb controls corn borer. For cotton bollworm and corn borer respectively, the correct pair is cryIAc and cryIAb. NCERT Ch 10, p.180.

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Frequently asked

What is Bt cotton in simple words?

Bt cotton is cotton that has been given a gene from the bacterium Bacillus thuringiensis. This gene makes the plant produce a toxin that kills insect pests like bollworms, so the plant protects itself.

What does 'Bt' stand for?

Bt stands for Bacillus thuringiensis, the soil bacterium whose cry gene (toxin gene) is transferred into the cotton plant.

Which cry gene is used in Bt cotton?

cryIAc (and cryIIAb) control cotton bollworms, so cryIAc is the key gene for Bt cotton. cryIAb is used for corn borer, not cotton.

What pests does Bt cotton control?

Mainly lepidopteran insect pests, especially cotton bollworms. Bt toxins are insect-group specific and do not affect nematodes or fungi.

How is Bt cotton different from RNAi crops?

Bt cotton makes a toxin protein that kills insects that eat it. RNAi crops silence a specific gene in a pest (for example a nematode) so the pest cannot survive. Bt = insect resistance; RNAi = nematode resistance.