Tobacco and Nicotine: Effects on the Heart and Lungs

Biology · Human Health and Diseases · NEET

Tobacco contains nicotine, an alkaloid. Nicotine makes the adrenal gland release adrenaline and nor-adrenaline into the blood, and these raise blood pressure and increase heart rate. Smoking also raises carbon monoxide in blood (so less oxygen reaches the body) and causes emphysema, bronchitis, coronary heart disease and cancer of the lung, throat and urinary bladder. Memory hook: "Nicotine hits the ADRENAL, adrenaline pushes the HEART; smoke chokes the LUNGS with CO."
How Tobacco Harms the Heart and LungsTobacco(nicotine)Adrenal glandreleases catecholaminesAdrenaline +nor-adrenalineup BP, up heart rateSmoke: CO upless haem-bound O2Emphysema, CHD,lung/throat cancerNCERT Ch7, Human Health and Disease
Nicotine stimulates the adrenal gland to release adrenaline and nor-adrenaline, raising blood pressure and heart rate; smoke raises carbon monoxide (less oxygen) and damages the lungs, causing emphysema, coronary heart disease and cancers.

Your doubts, answered

What exactly does nicotine do to the heart?

Nicotine does not act on the heart directly first. It stimulates the adrenal gland to release adrenaline (epinephrine) and nor-adrenaline (nor-epinephrine) into the blood. These two hormones raise blood pressure and increase the heart rate. This is the exact NCERT line and is a common NEET match-the-column point.

Why does smoking raise blood pressure and heart rate?

Because nicotine triggers the adrenal gland to pour adrenaline and nor-adrenaline (catecholamines) into the blood. These catecholamines make the heart beat faster and squeeze blood vessels, so blood pressure goes up. For NEET, link nicotine -> adrenal gland -> catecholamines -> high BP and fast heart.

Which gland does nicotine stimulate?

The adrenal gland. Nicotine stimulates the adrenal gland to release adrenaline and nor-adrenaline (together called catecholamines) into blood circulation. NEET 2026 tested this exact fact in a match-the-column question.

Is nicotine a stimulant or a depressant?

Nicotine acts as a stimulant type of drug because it activates the adrenal gland and speeds up the heart and blood pressure. Do not confuse it with heroin, which is a depressant that slows down body functions. Mixing these up is the main NEET trap in drug match questions.

What does carbon monoxide from smoking do?

Smoking increases carbon monoxide (CO) in the blood. CO binds haemoglobin and reduces the amount of haem-bound oxygen. This causes oxygen deficiency in the body. So a smoker's tissues get less oxygen even though breathing looks normal.

Which diseases does tobacco smoking cause?

NCERT lists cancer of the lung, urinary bladder and throat, plus bronchitis, emphysema, coronary heart disease and gastric ulcer. Tobacco chewing (not smoking) is linked to cancer of the oral cavity. Emphysema is the chronic lung disorder chiefly caused by cigarette smoking.

What is the difference between smoking and chewing tobacco for cancer?

Smoking is linked to cancer of the lung, urinary bladder and throat. Tobacco chewing is linked to cancer of the oral cavity (mouth). Both deliver nicotine, but the cancer site differs by how tobacco is used.

⚠️ The NEET trap
Nicotine is a depressant that slows down body functions, like heroin.
Nicotine stimulates the adrenal gland to release catecholamines (adrenaline and nor-adrenaline), which RAISE blood pressure and heart rate. Heroin is the depressant, not nicotine.
🧠 In drug match questions, NTA swaps nicotine and heroin. Remember: Nicotine = adrenal stimulant (BP up); Heroin = depressant (body slows down).

Real NEET questions

2026

Match List I with List II: List I (Drug): A. Nicotine B. Morphine C. Heroin D. Cocaine List II (Effect): I. Causes sense of euphoria and increased energy II. Stimulates adrenal gland to release catecholamines into blood circulation III. Effective sedative and painkiller IV. A depressant; slows down body function

A · A-III, B-II, C-IV, D-I
B · A-II, B-III, C-I, D-IV
C · A-II, B-III, C-IV, D-I
D · A-III, B-II, C-I, D-IV
Solution: Nicotine (A) stimulates the adrenal gland to release catecholamines (adrenaline/nor-adrenaline) into blood -> II. Morphine (B) is an effective sedative and painkiller -> III. Heroin (C) is a depressant that slows down body functions -> IV. Cocaine (D) gives euphoria and increased energy -> I. So A-II, B-III, C-IV, D-I, which is option (C).

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Frequently asked

Is nicotine an alkaloid?

Yes. NCERT states tobacco contains many chemicals including nicotine, which is an alkaloid. It is the active drug that causes tobacco addiction.

Why is emphysema linked to smoking?

Emphysema is a chronic disorder in which alveolar walls are damaged, so the respiratory surface for gas exchange decreases. NCERT names cigarette smoking as a major cause. It is a frequently asked one-line NEET fact.

Does smoking cause coronary heart disease (CHD)?

Yes. NCERT lists coronary heart disease among the conditions linked to smoking. Nicotine-driven high blood pressure and fast heart rate plus reduced oxygen strain the heart and blood vessels.

How many years has tobacco been used?

NCERT notes tobacco has been used by human beings for more than 400 years. It is smoked, chewed, or used as a snuff.

Why does smoking cause oxygen deficiency?

Smoking raises carbon monoxide (CO) in the blood. CO reduces the amount of haem-bound oxygen carried by haemoglobin, so tissues receive less oxygen and the body faces oxygen deficiency.