Prosthetic groups differ from co-enzymes in that :-
Answer: (B) they (prosthetic groups) are tightly bound to apoenzymes.. Answer: (B) they (prosthetic groups) are tightly bound to apoenzymes.
- A.they require metal ions for their activity.
- B.they (prosthetic groups) are tightly bound to apoenzymes.✓
- C.their association with apoenzymes is transient.
- D.they can serve as co-factors in a number of enzyme-catalyzed reactions.
Correct Answer
(B) they (prosthetic groups) are tightly bound to apoenzymes.
Solution & Explanation
Answer: (B) they (prosthetic groups) are tightly bound to apoenzymes. Solution: NCERT distinguishes the three cofactor types by how firmly they associate with the apoenzyme. Prosthetic groups are organic cofactors that are tightly bound to the apoenzyme (e.g., haem in catalase), whereas coenzymes associate only transiently during catalysis. Therefore the property that sets prosthetic groups apart from coenzymes is their tight binding to the apoenzyme. NCERT Reference: Ch 9, p.118, line ~6 — "Prosthetic groups are organic compounds and are distinguished from other cofactors in that they are tightly bound to the apoenzyme."