NEET 2024 · BiologyEnzymesPrevious Year Question

Regarding catalytic cycle of an enzyme action, select the correct sequential steps: A. Substrate enzyme complex formation. B. Free enzyme ready to bind with another substrate. C. Release of products. D. Chemical bonds of the substrate broken. E. Substrate binding to active site. Choose the correct answer from the options given below:

Answer: (D) E, A, D, C, B. Answer: (D) E, A, D, C, B.

  1. A.A, E, B, D, C
  2. B.B, A, C, D, E
  3. C.E, D, C, B, A
  4. D.E, A, D, C, B

Correct Answer

(D) E, A, D, C, B

Solution & Explanation

Answer: (D) E, A, D, C, B. Solution: Following the catalytic cycle, the substrate first binds to the active site (E), forming the substrate-enzyme complex (A); the active site then breaks the chemical bonds of the substrate (D); the products are released (C); leaving the free enzyme ready to bind another substrate (B). This ordered sequence E→A→D→C→B matches NCERT's four-step description of the catalytic cycle. NCERT Reference: Ch 9, p.115, line ~44 — "First, the substrate binds to the active site of the enzyme... breaks the chemical bonds of the substrate and the new enzyme-product complex is formed."

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