NEET 2019 Odisha · ChemistryProtein structurePrevious Year Question

Which structure(s) of proteins remain(s) intact during the denaturation process?

Answer: (B) Primary structure only. \textbf{Answer:} (B) Only the primary structure remains intact during denaturation.

  1. A.Both secondary and tertiary structures
  2. B.Primary structure only✓
  3. C.Secondary structure only
  4. D.Tertiary structure only

Correct Answer

(B) Primary structure only

Solution & Explanation

\textbf{Answer:} (B) Only the primary structure remains intact during denaturation. \textbf{Solution:} Denaturation disrupts the secondary and tertiary structures of a protein by breaking hydrogen bonds and other non-covalent interactions, causing loss of biological activity. The primary structure — the sequence of amino acids joined by covalent peptide bonds () — is not affected, since peptide bonds are not broken during denaturation. Hence only the primary structure remains intact, giving option B.

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