NEET 2019 Odisha · ChemistryProtein structurePrevious Year Question

Which structure(s) of proteins remain(s) intact during the denaturation process?

Answer: (B) Primary structure only. \textbf{Answer:} (B) Only the primary structure remains intact during denaturation.

  1. A.Both secondary and tertiary structures
  2. B.Primary structure only
  3. C.Secondary structure only
  4. D.Tertiary structure only

Correct Answer

(B) Primary structure only

Solution & Explanation

\textbf{Answer:} (B) Only the primary structure remains intact during denaturation. \textbf{Solution:} Denaturation disrupts the secondary and tertiary structures of a protein by breaking hydrogen bonds and other non-covalent interactions, causing loss of biological activity. The primary structure — the sequence of amino acids joined by covalent peptide bonds () — is not affected, since peptide bonds are not broken during denaturation. Hence only the primary structure remains intact, giving option B.

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