How does steroid hormone influence the cellular activities?
Answer: (B) Binding to DNA and forming a gene-hormone complex. Answer: (b) Binding to DNA and forming a gene-hormone complex Solution: Steroid hormones are lipid-soluble and interact with intracellular receptors.
- A.Changing the permeability of the cell membrane
- B.Binding to DNA and forming a gene-hormone complex✓
- C.Activating cyclic AMP located on the cell membrane
- D.Using aquaporin channels as second messenger
Correct Answer
(B) Binding to DNA and forming a gene-hormone complex
Solution & Explanation
Answer: (b) Binding to DNA and forming a gene-hormone complex Solution: Steroid hormones are lipid-soluble and interact with intracellular receptors. The hormone-receptor complex interacts with the genome (DNA) to regulate gene expression or chromosome function, producing the cellular response. They do not act via membrane second messengers like cyclic AMP, which is the route for protein/peptide hormones. NCERT Reference: Chapter 19, Page 248, Line(s) 13-16 — "Hormones which interact with intracellular receptors (e.g., steroid hormones, iodothyronines, etc.) mostly regulate gene expression or chromosome function by the interaction of hormone-receptor complex with the genome."
