Select the correct match.
Answer: (A) Sickle cell anaemia - Autosomal recessive trait, chromosome-11. Answer: (A) Sickle cell anaemia - Autosomal recessive trait, chromosome-11 Solution: Sickle-cell anaemia is an autosome-linked (autosomal) recessive trait affecting the beta-globin chain, whose gene HBB lies on chromosome 11.
- A.Sickle cell anaemia - Autosomal recessive trait, chromosome-11✓
- B.Thalassemia - X linked
- C.Haemophilia - Y linked
- D.Phenylketonuria - Autosomal dominant trait
Correct Answer
(A) Sickle cell anaemia - Autosomal recessive trait, chromosome-11
Solution & Explanation
Answer: (A) Sickle cell anaemia - Autosomal recessive trait, chromosome-11 Solution: Sickle-cell anaemia is an autosome-linked (autosomal) recessive trait affecting the beta-globin chain, whose gene HBB lies on chromosome 11. The other options are wrong: thalassemia is autosomal recessive (not X-linked), haemophilia is X-linked recessive (not Y-linked), and phenylketonuria is autosomal recessive (not dominant). NCERT Reference: NCERT Class XII, Ch 4, p.74, lines 019-021: "Sickle-cell anaemia : This is an autosome linked recessive trait that can be transmitted from parents to the offspring when both the partners are carrier for the gene (or heterozygous)."