NEET 2023 Phase 1 · BiologyPrevious Year Question
Which one of the following is the sequence on corresponding coding strand, if the sequence on mRNA formed is as follows 5' AUCGAUCGAUCGAUCGAUCG AUCG AUCG 3'?
Answer: (C) 5' ATCGATCGATCGATCGATCG ATCGATCG 3'. Answer: (C) 5' ATCGATCGATCGATCGATCG ATCGATCG 3'.
- A.5' UAGCUAGCUAGCUAGCUA GCUAGC UAGC 3'
- B.3' UAGCUAGCUAGCUAGCUA GCUAGCUAGC 5'
- C.5' ATCGATCGATCGATCGATCG ATCGATCG 3'✓
- D.3' ATCGATCGATCGATCGATCG ATCGATCG 5'
Correct Answer
(C) 5' ATCGATCGATCGATCGATCG ATCGATCG 3'
Solution & Explanation
Answer: (C) 5' ATCGATCGATCGATCGATCG ATCGATCG 3'. The coding strand has the same sequence and same 5'->3' polarity as the mRNA, except that thymine replaces uracil; so AUCG... becomes ATCG... in the 5'->3' direction. NCERT Ch 5, p.92, lines 008-009: "The other strand which has the polarity (5'->3') and the sequence same as RNA (except thymine at the place of uracil)... is referred to as coding strand."
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