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NEET 2025 · BiologyPrevious Year Question

Why can't insulin be given orally to diabetic patients?

Answer: (D) It will be digested in Gastro-Intestinal (GI) tract. Answer: (d) It will be digested in Gastro-Intestinal (GI) tract Solution: Insulin is a peptide hormone, and peptides/proteins are broken down by proteolytic enzymes in the gastro-intestinal tract.

  1. A.Because of structural variation
  2. B.Its bioavailability will be increased
  3. C.Human body will elicit strong immune response
  4. D.It will be digested in Gastro-Intestinal (GI) tract✓

Correct Answer

(D) It will be digested in Gastro-Intestinal (GI) tract

Solution & Explanation

Answer: (d) It will be digested in Gastro-Intestinal (GI) tract Solution: Insulin is a peptide hormone, and peptides/proteins are broken down by proteolytic enzymes in the gastro-intestinal tract. If taken orally it would be digested into its constituent amino acids and lose biological activity, so it must be administered by injection. NCERT Reference: Chapter 19, Page 245, Line(s) 42 — "Insulin is a peptide hormone, which plays a major role in the"

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