Avery, MacLeod, McCarty Experiments — NEET Biology
📚 Practice ConceptPrior to the work of Oswald Avery, Colin MacLeod and Maclyn McCarty (1933-44), the genetic material was thought to be a protein. They worked to determine the biochemical nature of 'transforming principle' in Griffith's experiment.
Consider the following statements regarding the biochemical characterisation of the transforming principle by Avery, MacLeod, and McCarty: S1. They concluded that DNA is the hereditary material responsible for transformation. S2. Treatment of the heat-killed S strain extract with protease prevented transformation. S3. Treatment of the heat-killed S strain extract with RNase destroyed the transforming ability. S4. Their work was a continuation of Frederick Griffith’s experiment to identify the nature of the transforming principle. S5. Before their experiment, RNA was widely believed to be the genetic material. Which of the following statements are NOT correct?
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