If a geneticist uses the blind approach for sequencing the whole genome of an organism, followed by assignment of functions to different segment, the methodology adopted by him is called as:

Solution & Explanation

Answer: (A) Sequence annotation. The 'blind approach' of sequencing the whole genome (all coding and non-coding DNA) first and later assigning functions to different regions is termed Sequence Annotation; the alternative was the Expressed Sequence Tags (ESTs) approach. NCERT Ch 5, p.103, lines 013-017: "The other took the blind approach of simply sequencing the whole set of genome that contained all the coding and non-coding sequence, and later assigning different regions in the sequence with functions (a term referred to as Sequence Annotation)."