Sample Questions β Amphibolic Pathway
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MCQ
Match the respiratory intermediates with their biosynthetic roles:
A. Acetyl CoA
B. Ξ±-Ketoglutarate
C. Glyceraldehyde-3-phosphate
D. Succinyl-CoA
1. Amino acid synthesis
2. Fatty acid synthesis
3. Heme synthesis
4. Entry point for glycolysis
β
Correct Answer: D
Each intermediate can be diverted into a specific biosynthetic pathway.
MCQ
Which of the following best explains the dual role of the respiratory pathway?
β
Correct Answer: C
Dual function = energy generation + raw materials for biosynthesis.
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MCQ
Why do proteins enter the respiratory pathway only after deamination?
β
Correct Answer: D
After deamination, the carbon chain of amino acids enters the pathway as pyruvate, acetyl-CoA or TCA intermediates.
MCQ
Why must respiration be flexible in utilising different substrates like carbs, proteins, and fats?
β
Correct Answer: B
Depending on nutritional status, different substrates are respired.
MCQ
Assertion (A): Fatty acids are directly broken into glyceraldehyde-3-phosphate during respiration.
Reason (R): Both glycerol and fatty acids enter glycolysis directly.
β
Correct Answer: C
Glycerol enters as PGAL, but fatty acids are first converted to acetyl-CoA (not PGAL).
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